陈 涛

发布时间:2016-04-21  浏览次数:460

 

陈涛特聘副教授,

中国及美国毒理学会会员,江苏省预防医学会青年委员,江苏省环境毒理学会委员,Environmental Disease编委,环境与职业医学青年编委

学历及学术经历:

2012-至今, 苏州大学医学部公共卫生学院

2010-2012, 英国纽卡斯尔大学,研究人员

2007-2009, 英国伯明翰大学生,研究人员

2006-2007, 美国得克萨斯州立大学,研究人员

2002-2005, 中国科学院动物研究所,博士

研究方向:

1. 环境化学物的非遗传毒性机制

2. 丙烯酰胺跨代遗传毒性机制


代表性学术成果:

1. Chen JH, Hang Zhang, Stanley Aniagu, Yan Jiang*,Chen T*. The effects of methionine on TCE-induced DNA methylation and mRNA expression changes in mouse liver. Mol Cell Toxicol. 2017, 13:59-64

2. Jiang Y, Chen JH, Yue C, Zhang H,Tong J, Li JX*, Chen T*. The role of miR-182-5p in hepatocarcinogenesis of trichloroethylene in mice. Toxicol Sci. 2016 Dec 24

3. Jiang Y, Chen JH, Yue C, Zhang H, Chen T*.Trichloroethylene-induced DNA methylation changes in male F344 rat liver. Chem Res Toxicol. 2016 Sep 21

4. Zhang H, Yao YG, Chen Y, Yue C, Chen JH, Jiang Y*, Chen T*. Crosstalk between AhR and wnt/β-catenin signal pathwaysin the cardiac developmental toxicity of PM2.5 in zebrafish embryos.Toxicology2016 May 20;355-356:31-38.

5. Jiang Y, Wang D, Zhang G, Wang G, Tong J*Chen T*. Disruption of cardiogenesis in human embryonic stem cells exposed to trichloroethylene. Environ Toxicol. 2015 Apr 6

6. Jiang Y, Chen JH, Tong J,Chen T*. Transcriptomic profiling of trichloroethylene exposure in malemouse liver. Genomics Data. 2015 Jan 140-2

7. Jiang Y, Chen JH, Tong J,Chen T*. Trichloroethylene-induced gene expression and DNA methylation changes in B6C3F1 mouse liver. Plos One. 2014 Dec 30

8. Chen T, Middleton FK, Falcon S, Reaper PM, Pollard JR, Curtin NJ.Development of pharmacodynamic biomarkers for ATR inhibitors.Mol Oncol. 2014 Oct 13. 

9. Chen T, Stephens P, Middleton F, Curtin NJ. Targeting the S and G2 Checkpoint. Drug Discov Today.2011 Dec 14.

10. Chen T, Williams T, Mally A, Hamberger C, Mirbahai L, Hickling K, Chipman JK*. Gene expression and epigenetic changes by furan in rat liver. Toxicology. 2011 Nov 3

11. Chen T, Mally A, Ozden S, Chipman JK. Low Doses of the Carcinogen Furan Alter Cell Cycle and Apoptosis Gene Expression in Rat Liver Independent of DNA Methylation. Environ Health Perspect. 2010 Nov;118(11):1597-602.

12. Chen T#, Zhang YL#, Jiang Y, Liu JH, Hou Y, Schatten H, Chen DY, Sun QY*. Interspecies nuclear transfer reveals that demethylation of specific repetitive sequences is determined by recipient ooplasm but not by donor intrinsic property in cloned embryos. Mol Reprod Dev. 2006 Mar;73(3):313

13. Zhang YL#, Chen T#, Jiang Y, Zhong ZS, Liu SZ, Hou Y, Schatten H, Chen DY, Sun QY*. Active demethylation of individual genes in intracytoplasmic sperm injection rabbit embryos. Mol Reprod Dev. 2005 Dec;72(4):530-3

14. Chen T, Jiang Y, Zhang YL, Liu JH, Hou Y, Schatten H, Chen DY, Sun QY*. DNA hypomethylation of individual sequences in aborted cloned bovine fetuses. Front. Biosci. 2005, 10:3002-3008

15. Chen T#, Zhang YL#, Jiang Y, Liu SZ, Schatten H, Chen DY, Sun QY*. The DNA methylation events in normal and cloned rabbit embryos. FEBS Letters. 2004, 578


专利:Method for measuring ATR inhibition mediated increases in DNA damage. (2015.04.07,U.S. Patent Number 8999632


教学工作:

承担五年制预防医学生专业必修课《卫生毒理学》全英文教学课程,以及选修课《遗传毒理学》、《高级毒理学》、《临床毒理学》纳米世界等课程的授课。


联系方式

   联系电话:0512-65882273    邮箱:tchen@suda.edu.cn

版权所有 © 苏州大学医学部公共卫生学院

地址:苏州工业园区仁爱路199号 邮编:215123 电话:0512-65883323