裴育芳

发布时间:2016-04-21  浏览次数:942




裴育芳(1984.5-),女,山西晋城人;副教授。


【教育经历】

2001.9-2005.7  西安交通大学理学院数学与应用数学专业   学士

2005.9-2010.9  西安交通大学生命科学与技术学院生物化学与分子生物学专业  博士

2007.4-2010.1  美国密苏里大学堪萨斯分校(UMKC)  访问学者


【工作经历】

2010.10-2013.12  上海理工大学系统生物医学研究中心  助理研究员

2012.3-2013.6  美国杜兰大学(Tulane University)生物统计系  博士后

2014.6-至今  苏州大学公共卫生学院  副教授


【研究方向】

生物统计学、遗传流行病学。

主要从事统计遗传学方法研究及以肥胖症为代表的复杂疾病遗传定位研究。


【研究课题】

1)国家自然科学基金面上项目,31770417、整合宿主遗传和肠道菌群数据探索肥胖症遗传机制的方法与应用研究、2018/01-2021/1259万元、在研、主持。

2)国家自然科学基金青年科学基金项目,31501026、全基因组双变量meta分析鉴定肥胖症和骨质疏松症多效易感基因的方法与应用研究、2016/01-2018/1224万元、在研、主持。

3)江苏省自然科学基金青年项目,BK20150323、肥胖症候选基因NLK致病突变的定位及作用机制研究、2015/07-2018/0620万元、在研、主持。

4) 教育部留学回国人员科研启动基金,新型Meta分析检测肥胖症易感基因、3万元、在研、主持。


【代表性论文】

1) Pei YF, Hu WZ, Yan MW, Li CW, Liu L, Yang XL, Hai R, Wang XY, Shen H, Tian Q, Deng HW,Zhang L.Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density.Bone. 2018;110:378-385.

2) Pei YF, Ren HG, Liu L, Li X, Fang C, Huang Y, Hu WZ, Kong WW, Feng AP, You XY, Zhao W, Shen H, Tian Q, Zhang YH, Deng HW, Zhang L. Genomic variants at 20p11 associated with body fat mass in the European population. Obesity. 2017;25(4):757-764.

3) Pei YF, Hu WZ, Hai R, Wang XY, Ran S, Lin Y, Shen H, Tian Q; GEFOS-seq Consortium; AOGC Consortium; UK10K Consortium, Lei SF, Zhang YH, Papasian CJ, Deng HW, Zhang L. Genome-wide association meta-analyses identified 1q43 and 2q32.2 for hip Ward's triangle areal bone mineral density. Bone. 2016;91:1-10.

4) Pei YF, Xie ZG, Wang XY, Hu WZ, Li LB, Ran S, Lin Y, Hai R, Shen H, Tian Q, Zhang YH, Lei SF, Papasian CJ, Deng HW, Zhang L. Association of 3q13.32 variants with hip trochanter and intertrochanter bone mineral density identified by a genome-wide association study. Osteoporos Int. 2016; 27(11):3343-54.

5) Pei YF, Tian Q, Zhang L, Deng HW. Exploring the Major Sources and Extent of Heterogeneity in a Genome-Wide Association Meta-Analysis. Ann Hum Genet. 2016 Mar;80(2):113-22.

6) Zhang L, Shen YP, Hu WZ, Ran S, Lin Y, Lei SF, Zhang YH, Papasian CJ, Yi N, Pei YF. A new method for estimating effect size distribution and heritability from genome-wide association summary results. Hum Genet. 2016 Feb;135(2):171-84.

7) Pei YF, Liu YJ, Zhang L, Li J, Shen H, Liu YZ, Tian Q, He H, Wu SY, Ran S,

Han YY, Hai R, Lin Y, Zhu JY, Zhu XZ, Papasian CJ, Deng HW. Meta-analysis of

genome-wide association data identifies novel susceptibility loci for obesity. Hum

Mol Genet. 2014; 23(3):820-30.

8) Pei YF, Zhang L, Papasian CJ, Deng HW. On individual genome-wide association studies and their meta-analysis. Hum Genet. 2014;133(3):265-79.

9) Zhang L*, Pei YF*, Wang YP, Papasian CJ, Deng HW*. FISH: Fast and accurate diploid genotype imputation via segmental hidden Markov model. Bioinformatics.2014; 30(13):1876-83. (*: 通讯作者)


【教学工作】

承担医学本科生的医学统计学、医学统计软件包、和循证医学等课程的教学工作;参加教材编写1部。


【联系方式】

联系电话:0512-65880079       邮箱:ypei@suda.edu.cn




Curriculum Vitae


[GENERAL INFORMATION]

NameYu-Fang Pei    GenderFemale

Phone86-051265880079  Emailypei@suda.edu.cn

Research Direction: Biostatistics, bioinformatics, genetic epidemiology.


[EDUCATION]

2001.9 – 2005.7 B.S. in Mathematics and Applied Mathematics, School of Science, Xi’an Jiaotong University Xi’an, Shannxi, P. R. China.

2007.4 - 2010.1. Visiting Student in School of Medicine, University of Missouri-Kansas City, Kansas City, Missouri, USA.

2005.9 – 2010.9 Ph. D. in Biochemistry and Molecular Biology, School of Life Science & Technology, Xi’an Jiaotong University, Xi’an, Shaanxi, P. R. China.


[EMPLOYMENT]

2014.6 – Present, Department of Epidemiology & Statistics, School of Public Health, Soochow University. Associate Professor

2012.2 – 2013.7 Department of bioinformatics and biostatistics, Tulane University. Post Doctor.

2010.10 – 2013.12 Center of system biomedical sciences, university of Shanghai for Science and Technology, Research Assistant.


[GRANTS]

1) The National Natural Science Foundation of China, 31770417, Methodology and Application Research of Integrating Host Genetics and Gut Microbiome Data to Explore Obesity Genetic Mechanis, 2018/01-2021/12, PI.

2) The National Natural Science Foundation of China, 31501026, Methodology and Application Research of Bivariate Genome-wide meta-analysis for the Identification of Pleiotropic Genes for Obesity and Osteoporosis, 2016/01-2018/12, PI.

3) The Natural Science Foundation of Jiangsu Province, BK20150323, Identification and Effect Mechanism Research of Obesity Candidate Gene NLK Causal Mutation, 2015/07-2018/06, PI.


[PUBLICATIONS]

1) Pei YF, Hu WZ, Yan MW, Li CW, Liu L, Yang XL, Hai R, Wang XY, Shen H, Tian Q, Deng HW, Zhang L. Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density. Bone. 2018;110:378-385.

2) Pei YF, Ren HG, Liu L, Li X, Fang C, Huang Y, Hu WZ, Kong WW, Feng AP, You XY, Zhao W, Shen H, Tian Q, Zhang YH, Deng HW, Zhang L. Genomic variants at 20p11 associated with body fat mass in the European population. Obesity. 2017;25(4):757-764.

3) Pei YF, Hu WZ, Hai R, Wang XY, Ran S, Lin Y, Shen H, Tian Q; GEFOS-seq Consortium; AOGC Consortium; UK10K Consortium, Lei SF, Zhang YH, Papasian CJ, Deng HW, Zhang L. Genome-wide association meta-analyses identified 1q43 and 2q32.2 for hip Ward's triangle areal bone mineral density. Bone. 2016;91:1-10.

4) Pei YF, Xie ZG, Wang XY, Hu WZ, Li LB, Ran S, Lin Y, Hai R, Shen H, Tian Q, Zhang YH, Lei SF, Papasian CJ, Deng HW, Zhang L. Association of 3q13.32 variants with hip trochanter and intertrochanter bone mineral density identified by a genome-wide association study. Osteoporos Int. 2016; 27(11):3343-54.

5) Pei YF, Tian Q, Zhang L, Deng HW. Exploring the Major Sources and Extent of Heterogeneity in a Genome-Wide Association Meta-Analysis. Ann Hum Genet. 2016 Mar;80(2):113-22.

6) Zhang L, Shen YP, Hu WZ, Ran S, Lin Y, Lei SF, Zhang YH, Papasian CJ, Yi N, Pei YF. A new method for estimating effect size distribution and heritability from genome-wide association summary results. Hum Genet. 2016 Feb;135(2):171-84.

7) Pei YF, Liu YJ, Zhang L, Li J, Shen H, Liu YZ, Tian Q, He H, Wu SY, Ran S,

Han YY, Hai R, Lin Y, Zhu JY, Zhu XZ, Papasian CJ, Deng HW. Meta-analysis of

genome-wide association data identifies novel susceptibility loci for obesity. Hum

Mol Genet. 2014; 23(3):820-30.

8) Pei YF, Zhang L, Papasian CJ, Deng HW. On individual genome-wide association studies and their meta-analysis. Hum Genet. 2014;133(3):265-79.

9) Zhang L*, Pei YF*, Wang YP, Papasian CJ, Deng HW*. FISH: Fast and accurate diploid genotype imputation via segmental hidden Markov model. Bioinformatics.2014; 30(13):1876-83. (*: Corresponding author)


[TEACHING]

Biostatistics, Medical Research Approach, Evidence-based medicine



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