信丽丽

发布时间:2018-03-26  浏览次数:397

信丽丽

姓名:信丽丽(1987.4-

 1.学历

 2008.09–2012.06华中科技大学博士研究生

 2004.09–2008.06华中师范大学大学本科


 2.工作经历和任职情况

 2015.07-至今苏州大学公共卫生学院副教授

 2012.08–2015.06苏州大学公共卫生学院 讲师


 3.研究方向

环境毒理学,细胞对环境污染物的应激反应


 4.承担课题情况

主持国家自然科学基金青年科学基金、江苏省基础研究计划(自然科学基金)-青年基金、中国博士后科学基金、江苏省高校自然科学研究面上项目各一项


 5.发表论文情况

 1) Jianshu Wang, Bizhong Che, Leshuai W. Zhang, Guangzhu Dong, Qiulin Luo, Lili Xin*,Comparative genotoxicity of silver nanoparticles in human liver HepG2 and lung epithelial A549 cells, J Appl Toxicol, 2017, 37(4):495-501

 2) Bizhong Che, Qiulin Luo, Bingzhong Zhai, Guoqiang Fan, Zhiyong Liu, Kaiming Cheng,Lili Xin*, Cytotoxicity and genotoxicityof nanosilver in stable GADD45α promoter-driven luciferase reporter HepG2 and A549 cells, Environ Toxicol, 2017, 32(9): 2203-11

 3) Lili Xin*,Jianshu Wang, Leshuai W. Zhang, Bizhong Che, Guangzhu Dong, Guoqiang Fan, Kaiming Cheng,Development of HSPA1A promoter-driven luciferase reporter gene assays in human cells for assessing the oxidative damage induced by silver nanoparticles, Toxicol Appl Pharmacol, 2016, 304:9-17

 4)Lili Xin*,Jianshu Wang, Guoqiang Fan, Bizhong Che, Kaiming Cheng, Guangzhu Dong, Comparative oxidative stress elicited by nanosilver in stable HSPA1A promoter-driven luciferase reporter HepG2 and A549 cells, Toxicol Res, 2016, 5(5):1298-305

 5) Lili Xin,Jianshu Wang, Guoqiang Fan, Bizhong Che, Yanhu Wu, Sifan Guo, Jian Tong*,Oxidative stress and mitochondrial injury mediated cytotoxicity induced by silver nanoparticles in human A549 and HepG2 cells, Environ Toxicol, 2016, 31(12):1691-9

 6) Lili Xin*,Jianshu Wang, Yanhu Wu, Sifan Guo, The development of GADD45α luciferase reporter assays in human cells for assessing the genotoxicity of environmental pollutants, Toxicol Mech Methods, 2015, 25(2):136-42

 7) Lili Xin, Jianshu Wang, Yanhu Wu, Sifan Guo, Jian Tong*,Increased oxidative stress and activated heat shock proteins in human cell lines by silver nanoparticles, Hum Exp Toxicol, 2015, 34(3):315-23

 8) Lili Xin*, Jianshu Wang, Guoqiang Fan, Yanhu Wu, Sifan Guo,Activation of HSPA1Apromoter by environmental pollutants: an early and rapid response to cellular damage, Environ Toxicol Pharmacol, 2015, 39(3):1027-33

 9) Lili Xin, Yao Lin, Aiqing Wang, Wei Zhu, Yu Liang, Xiaojun Su, Chengjiao Hong, Jianmei Wan, Yarong Wang, Hailin Tian*, Cytogenetic evaluation for the genotoxicity of bisphenol-A in Chinese hamster ovary cells, Environmental Toxicology and Pharmacology, 2015, 40(2):524-29

 10) Lili Xin, Jianshu Wang, Sifan Guo, Yanhu Wu, Xiaohai Li, Huaxin Deng, Dan Kuang, Wei Xiao, Tangchun Wu, Huan Guo*, Organic extracts of coke oven emissions can induce genetic damage in metabolically competent HepG2 cells, Environ Toxicol Pharmacol, 2014, 37(3): 946-53

 11) Lili Xin, Xiaohai Li, Huaxin Deng, Dan Kuang, Xiayun Dai, Suli Huang, Feng Wang,Meian He,R. William Currie, Tangchun Wu*, Development of stable HSPA1A promoter-driven luciferase reporter HepG2 cells for assessing the toxicity of organic pollutants present in air, Cell Stress Chaperones, 2012, 17(5):567-76

 12)张天翊,车碧众,罗秋林,翟兵中,董广柱,信丽丽*,纳米银颗粒对人HepG2A549细胞的氧化损伤效应研究,环境与健康杂志, 2017, 34(10): 854 ~857

 13)车碧众,董广柱,信丽丽*,热休克蛋白基因启动子报告基因技术评估环境污染物毒性作用的研究进展,癌变畸变突变, 2017, 29(6): 476 ~78

 14)信丽丽*,车碧众,武艳虎,郭思梵,焦炉逸散物和汽车尾气有机提取物对人肝癌细胞的遗传毒性作用,癌变畸变突变, 2015, 27(4): 299~ 303

 15)信丽丽,李晓海,邓华欣,旷聃,戴霞云,黄素丽,王峰,何美安, Currie RW,邬堂春*, HSPA1A启动子荧光素酶报告基因HepG2细胞的构建及其在职业环境污染物毒性评估中的应用,中华劳动卫生职业病杂志, 2012, 30(12): 883~ 87

 16)Neng Chen, Lili Xin, Lingmei Zhou, Jinbo Cheng, Liqiang Qin, Shufen Han, Qiang Shen,Zhongxiao Wan*, Depot-specific effects of treadmill running and rutin on white adipose tissue function in diet induced obese mice, Journal of Physiology & Biochemistry. 2016, 72(3): 1-15

 17)Xiaohai Li, Yingying Feng, Huaxin Deng, Wangzhen Zhang, Dan Kuang, Qifei Deng, Xiayun Dai, Dafeng Lin, Suli Huang, Lili Xin, Yunfeng He, Kun Huang, Meian He, Xiaomin Zhang, Tangchun Wu*,The Dose–Response Decrease in Heart Rate Variability:Any Association with the Metabolites of PolycyclicAromatic Hydrocarbons in Coke Oven Workers? PlOS One, 2012, 7(9):e44562

 18) Yanying Duan, Suli Huang, Jin Yang, Piye Niu, Zhiyong Gong, Xiaoyong Liu, Lili Xin, R. William Currie, Tangchun Wu*, HspA1A facilitates DNA repair in human bronchial epithelia cells exposed to benzo[a]pyrene and interacts with casein kinase 2, Cell Stress and Chaperone, 2014, 19(2):271-9

 6.联系方式

联系电话:0512-65880074邮箱:llxin@suda.edu.cn

Xin Lili

NameXin Lili (1987.4-)

Education

 2008.09-2012.06 Huazhong University of Science & Technology Doctor (Medicine, Occupational and Environmental Health)

 2004.09-2008.06 Central China Normal University Bachelor (Biology Science)

Working Experience

 2015.07-Present Department of occupational and environmental health, School of public health, Soochow University, Associate professor

 2012.08-2015.06 Department of occupational and environmental health, School of public health, Soochow University,  Lecture


Research Direction

 Environmental toxicology, cell stress to environmental pollutants

Grants

 National Natural Scientific Foundation of China grant (81402705), the Natural Science Foundation of Jiangsu Province (BK20140367), the Natural Science Foundation of the Jiangsu Higher Education Institutions of China (13KJB330008), and the China Postdoctoral Science Foundation (2013M541728)

Publications:

 1) Jianshu Wang, Bizhong Che, Leshuai W. Zhang, Guangzhu Dong, Qiulin Luo, Lili Xin*,Comparative genotoxicity of silver nanoparticles in human liver HepG2 and lung epithelial A549 cells, J Appl Toxicol, 2017, 37(4):495-501

 2) Bizhong Che, Qiulin Luo, Bingzhong Zhai, Guoqiang Fan, Zhiyong Liu, Kaiming Cheng,Lili Xin*, Cytotoxicity and genotoxicityof nanosilver in stable GADD45α promoter-driven luciferase reporter HepG2 and A549 cells, Environ Toxicol, 2017, 32(9): 2203-11

 3) Lili Xin*,Jianshu Wang, Leshuai W. Zhang, Bizhong Che, Guangzhu Dong, Guoqiang Fan, Kaiming Cheng,Development of HSPA1A promoter-driven luciferase reporter gene assays in human cells for assessing the oxidative damage induced by silver nanoparticles, Toxicol Appl Pharmacol, 2016, 304:9-17

 4)Lili Xin*,Jianshu Wang, Guoqiang Fan, Bizhong Che, Kaiming Cheng, Guangzhu Dong, Comparative oxidative stress elicited by nanosilver in stable HSPA1A promoter-driven luciferase reporter HepG2 and A549 cells, Toxicol Res, 2016, 5(5):1298-305

 5) Lili Xin,Jianshu Wang, Guoqiang Fan, Bizhong Che, Yanhu Wu, Sifan Guo, Jian Tong*,Oxidative stress and mitochondrial injury mediated cytotoxicity induced by silver nanoparticles in human A549 and HepG2 cells, Environ Toxicol, 2016, 31(12):1691-9

 6) Lili Xin*,Jianshu Wang, Yanhu Wu, Sifan Guo, The development of GADD45α luciferase reporter assays in human cells for assessing the genotoxicity of environmental pollutants, Toxicol Mech Methods, 2015, 25(2):136-42

 7) Lili Xin, Jianshu Wang, Yanhu Wu, Sifan Guo, Jian Tong*,Increased oxidative stress and activated heat shock proteins in human cell lines by silver nanoparticles, Hum Exp Toxicol, 2015, 34(3):315-23

 8) Lili Xin*, Jianshu Wang, Guoqiang Fan, Yanhu Wu, Sifan Guo,Activation of HSPA1Apromoter by environmental pollutants: an early and rapid response to cellular damage, Environ Toxicol Pharmacol, 2015, 39(3):1027-33

 9) Lili Xin, Yao Lin, Aiqing Wang, Wei Zhu, Yu Liang, Xiaojun Su, Chengjiao Hong, Jianmei Wan, Yarong Wang, Hailin Tian*, Cytogenetic evaluation for the genotoxicity of bisphenol-A in Chinese hamster ovary cells, Environmental Toxicology and Pharmacology, 2015, 40(2):524-29

 10) Lili Xin, Jianshu Wang, Sifan Guo, Yanhu Wu, Xiaohai Li, Huaxin Deng, Dan Kuang, Wei Xiao, Tangchun Wu, Huan Guo*, Organic extracts of coke oven emissions can induce genetic damage in metabolically competent HepG2 cells, Environ Toxicol Pharmacol, 2014, 37(3): 946-53

 11) Lili Xin, Xiaohai Li, Huaxin Deng, Dan Kuang, Xiayun Dai, Suli Huang, Feng Wang,Meian He,R. William Currie, Tangchun Wu*, Development of stable HSPA1A promoter-driven luciferase reporter HepG2 cells for assessing the toxicity of organic pollutants present in air, Cell Stress Chaperones, 2012, 17(5):567-76

 12)张天翊,车碧众,罗秋林,翟兵中,董广柱,信丽丽*,纳米银颗粒对人HepG2A549细胞的氧化损伤效应研究,环境与健康杂志, 2017, 34(10): 854 ~857

 13)车碧众,董广柱,信丽丽*,热休克蛋白基因启动子报告基因技术评估环境污染物毒性作用的研究进展,癌变畸变突变, 2017, 29(6): 476 ~78

 14)信丽丽*,车碧众,武艳虎,郭思梵,焦炉逸散物和汽车尾气有机提取物对人肝癌细胞的遗传毒性作用,癌变畸变突变, 2015, 27(4): 299~ 303

 15)信丽丽,李晓海,邓华欣,旷聃,戴霞云,黄素丽,王峰,何美安, Currie RW,邬堂春*, HSPA1A启动子荧光素酶报告基因HepG2细胞的构建及其在职业环境污染物毒性评估中的应用,中华劳动卫生职业病杂志, 2012, 30(12): 883~ 87

 16)Neng Chen, Lili Xin, Lingmei Zhou, Jinbo Cheng, Liqiang Qin, Shufen Han, Qiang Shen,Zhongxiao Wan*, Depot-specific effects of treadmill running and rutin on white adipose tissue function in diet induced obese mice, Journal of Physiology & Biochemistry. 2016, 72(3): 1-15

 17)Xiaohai Li, Yingying Feng, Huaxin Deng, Wangzhen Zhang, Dan Kuang, Qifei Deng, Xiayun Dai, Dafeng Lin, Suli Huang, Lili Xin, Yunfeng He, Kun Huang, Meian He, Xiaomin Zhang, Tangchun Wu*,The Dose–Response Decrease in Heart Rate Variability:Any Association with the Metabolites of PolycyclicAromatic Hydrocarbons in Coke Oven Workers? PlOS One, 2012, 7(9):e44562

 18) Yanying Duan, Suli Huang, Jin Yang, Piye Niu, Zhiyong Gong, Xiaoyong Liu, Lili Xin, R. William Currie, Tangchun Wu*, HspA1A facilitates DNA repair in human bronchial epithelia cells exposed to benzo[a]pyrene and interacts with casein kinase 2, Cell Stress and Chaperone, 2014, 19(2):271-9

Contact

 Phone: 0512-65880074         Email: llxin@suda.edu.cn



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