黄一帆 男 讲师
电子邮箱：yyzhyf@hotmail.com; yyzhyf@suda.edu.cn
通讯地址：苏州工业园区仁爱路199号苏州大学一期医学楼医学部公共卫生学院402号2415室, 邮编215123
个人简介
黄一帆，医学博士，讲师
学习经历
2009.09-2014.07哈尔滨医科大学营养与食品卫生学医学博士
2004.09-2009.07厦门大学预防医学医学学士
2004.09-2009.07厦门大学生物科学理学学士（双学位）
工作经历
2015.11 至今, 苏州大学苏州医学院, 讲师
2014.09-2015.10 加拿大西安大略大学舒立克医学与牙学院，博士后
学术任职
1. 中国营养保健食品协会体重管理专业委员会委员
2. 江苏省毒理学会管理毒理与风险评估专业委员会委员
3. 苏州市预防医学会第二届职业卫生专业委员会委员
4. 苏州抗衰老学会内分泌代谢专业委员会委员
5. Frontiers in Nutrition(SCIE, JCR Q1) 客座编辑
研究方向
1. 糖尿病、肥胖等代谢性疾病及其心血管并发症的流行病学和发病机制研究，以及微量营养素、植物化学物质和传统中医药对其的防治作用。
2. 脓毒症发病机制和防治策略研究。
科研项目
1. 苏州市科技计划项目，当归补血汤对慢性代谢性疾病相关心肌损伤的保护作用应用基础研究，SKY2023119，2023.07 – 2026.06, 5万元，主持。
2. 苏州市科技计划项目，心肌氨基丁酸转氨酶保护线粒体功能并抵抗糖尿病心肌病的机制研究，SYS201708，2017.07 – 2020.06，5万元，主持。
3. 中国博士后科学基金面上项目，心肌氨基丁酸转氨酶低表达导致糖尿病心肌病的机制研究，2017M611909，2017.05 – 2020.06，5万元，主持。
4. 江苏省自然科学基金青年项目，Junctophilin-2对心脏脂中毒过程中内质网应激和细胞凋亡的保护作用和机制研究，BK20160331，2016.07 – 2019.06，20万元，主持。
专利
1. 发明专利：可诱导的转基因小鼠心肌病动物模型的构建方法及应用 (ZL201711001389.1)
代表性论文（*通讯作者）：
1. X. Y. Ji, Y. F. Huang, J. X. Wang, Z. F. Dong, R. Ni, Z. J. Su, D. Zheng, G. C. Fan, D. L. Jones, L. S. Song, S. Chakrabarti, J. X. Song, Z. L. Su, T. Q. Peng. JP2 and JCN Crosstalk Abrogate MURF1-Mediated JCN Ubiquitination and Degradation in Cardiomyocytes. JACC: Basic to Translational Science. 2026;11(5):101534.
2. M. Z. Cai, X. Jiang, X. Y. Xu, S. D. Zhao, Y. Sun, Y. S. Yang, P. Yang, C. Fang, Y. F. Huang*. Integrating adipsin with novel cardiometabolic and inflammatory indices for enhanced early prediction of gestational diabetes mellitus: a prospective cohort study. Cardiovascular Diabetology. 2025;24(1):189.
3. M. Z. Cai, X. Jiang, X. Y. Xu, S. D. Zhao, Y. Sun, Y. S. Yang, Y. Gu, Y. F. Huang*. Associations of vitamin D with lipid metabolism, inflammation, and mortality vary by glycemic status and gender: a nationwide prospective study. Frontiers in Nutrition. 2025;12:1597527.
4. S. Z. Yuan, H. Y. Shi, Y. Cui, Y. Liu, M. Z. Cai, Y. F. Huang*.Enhanced Rapid Screening for Multidrug-resistant tuberculosis through combined cardiometabolic and inflammatory indices: a cross-sectional study. Scientific Reports. 2024;14(1):1–7.
5. Y. F. Huang, M. H. Cheng, X. Y. Wang, H. L. Dong, J. Gao. Dang Gui Bu Xue Tang, a conventional Chinese herb decoction, ameliorates radiation-induced heart diseasevia Nrf2/HMGB1 pathway. Frontiers in Pharmacology. 2023;13:1086206.
6. M. Z. Cai, Y. M. Wang, T. T. Liu, Y. F. Huang*. Interaction between Vitamin D Status and Calcium Intake in Association with Blood Pressure and Hypertension. Journal of Nutritional Science and Vitaminology. 2023;69(2):81–9.
7. Y. F. Huang, G. Wang, T. Q. Peng. Calpain Activation and Organ Failure in Sepsis: Molecular Insights and Therapeutic Perspectives. Shock. 2021;56(1):5–15.
8. B. N. Chen, Y. F. Huang, D. Zheng, R. Ni, M. A. Bernards. Dietary Fatty Acids Alter Lipid Profiles and Induce Myocardial Dysfunction without Causing Metabolic Disorders in Mice. Nutrients. 2018;10(1):106.
9. X. Yang, Y. F. Huang, C. H. Sun, J. Li. Maternal Prenatal Folic Acid Supplementation Programs Offspring Lipid Metabolism by Aberrant DNA Methylation in Hepatic and Adipose in Rats. Nutrients. 2017;9(9):935.
10. M. Cai, Y. Huang, X. Sun, Y. He, C. Sun. Siesta is associated with reduced systolic blood pressure level and decreased prevalence of hypertension in older adults. Journal of Human Hypertension. 2016;30(3):216–8.
11. Y. F. Huang, T. T. Liu, C. H. Sun. Little beneficial effect of maternal vitamin supplement on metabolic disturbances in the offspring from the obese mother mice. Journal of Maternal-Fetal & Neonatal Medicine. 2015;28(3):272–5.
12. Y. F. Huang, Y. H. He, X. W. Sun, Y. J. He, Y. Li, C. H. Sun. Maternal High Folic Acid Supplement Promotes Glucose Intolerance and Insulin Resistance in Male Mouse Offspring Fed a High-Fat Diet. International Journal of Molecular Sciences. 2014;15(4):6298–313.
13. Y. F. Huang, X. X. Li, M. Q. Wang, H. Ning, A. Lima, Y. Li, C. H. Sun. Lipoprotein lipase links vitamin D, insulin resistance, and type 2 diabetes: a cross-sectional epidemiological study. Cardiovascular Diabetology. 2013;12(1):17.
English Profile
Yifan Huang, Male, Lecturer
Email: yyzhyf@hotmail.com; yyzhyf@suda.edu.cn
Address: Room 2415, Building 402, School of Public Health, Suzhou Medical College of Soochow University, 199 Ren'ai Road, Suzhou Industrial Park, Suzhou, Jiangsu 215123, China
Brief Introduction
Yifan Huang, Ph.D. in Medicine, Lecturer
(1)ORCID: https://orcid.org/0000-0002-5905-8165
(2) WoS Researcher ID: KYQ-5138-2024
(3) Frontiers Loop: https://loop.frontiersin.org/people/2075880/
Education
Sep 2009 - Jul 2014, Harbin Medical University | Nutrition and Food Hygiene | Ph.D. in Medicine
Sep 2004 - Jul 2009, Xiamen University | Preventive Medicine | Bachelor of Medicine
Sep 2004 - Jul 2009, Xiamen University | Biological Sciences | Bachelor of Science(Dual Degree)
Work Experience
Nov 2015 - Present, Suzhou Medical College of Soochow University | Lecturer
Sep 2014 - Oct 2015, Schulich School of Medicine & Dentistry, Western University, Canada | Postdoctoral Fellow
Academic Service and Professional Memberships
1. Member, Weight Management Specialty Committee, China Nutrition and Health Food Association (CNHFA)
2. Member, Regulatory Toxicology and Risk Assessment Specialty Committee, Jiangsu Society of Toxicology
3. Member, Occupational Health Specialty Committee, Suzhou Preventive Medicine Association
4. Member, Endocrine and Metabolic Specialty Committee, Suzhou Anti-aging Association
5. Guest Editor, Frontiers in Nutrition (SCIE, JCR Q1)
Research Interests
1. Epidemiological and pathogenic research on metabolic diseases (e.g., diabetes and obesity) and their cardiovascular complications, as well as the preventive and therapeutic effects of micronutrients, phytochemicals, and traditional Chinese medicine.
2. The pathogenesis and prevention strategies of sepsis.
Research Grants
1. The Protective Effects of Danggui Buxue Decoction Against Myocardial Injury Related to Chronic Metabolic Diseases, Suzhou Science and Technology Project (SKY2023119, 50,000 RMB), Principal Investigator, 2023.07 – 2026.06.
2. The Mechanism of Myocardial GABA Transaminase in Preserving Mitochondrial Function and Counteracting Diabetic Cardiomyopathy, Suzhou Science and Technology Project (SYS201708, 50,000 RMB), Principal Investigator, 2017.07 – 2020.06.
3. The Mechanism of Diabetic Cardiomyopathy Induced by Decreased Myocardial ABAT Expression, China Postdoctoral Science Foundation (2017M611909, 50,000 RMB), Principal Investigator, 2017.05 – 2020.06.
4. The Protective Role and Mechanisms of Junctophilin-2 in Endoplasmic Reticulum Stress and Apoptosis During Cardiac Lipotoxicity, Natural Science Foundation of Jiangsu Province (BK20160331, 200,000 RMB), Principal Investigator, 2016.07 – 2019.06.
Patent
1. Invention Patent: Method for constructing and application of an inducible transgenic mouse model of cardiomyopathy (ZL201711001389.1)
Publications (*Corresponding author)
1. X. Y. Ji, Y. F. Huang, J. X. Wang, Z. F. Dong, R. Ni, Z. J. Su, D. Zheng, G. C. Fan, D. L. Jones, L. S. Song, S. Chakrabarti, J. X. Song, Z. L. Su, T. Q. Peng. JP2 and JCN Crosstalk Abrogate MURF1-Mediated JCN Ubiquitination and Degradation in Cardiomyocytes. JACC: Basic to Translational Science. 2026;11(5):101534.
2. M. Z. Cai, X. Jiang, X. Y. Xu, S. D. Zhao, Y. Sun, Y. S. Yang, P. Yang, C. Fang, Y. F. Huang*. Integrating adipsin with novel cardiometabolic and inflammatory indices for enhanced early prediction of gestational diabetes mellitus: a prospective cohort study. Cardiovascular Diabetology. 2025;24(1):189.
3. M. Z. Cai, X. Jiang, X. Y. Xu, S. D. Zhao, Y. Sun, Y. S. Yang, Y. Gu, Y. F. Huang*. Associations of vitamin D with lipid metabolism, inflammation, and mortality vary by glycemic status and gender: a nationwide prospective study. Frontiers in Nutrition. 2025;12: 1597527.
4. S. Z. Yuan, H. Y. Shi, Y. Cui, Y. Liu, M. Z. Cai, Y. F. Huang*.Enhanced Rapid Screening for Multidrug-resistant tuberculosis through combined cardiometabolic and inflammatory indices: a cross-sectional study. Scientific Reports. 2024;14(1):1–7.
5. Y. F. Huang, M. H. Cheng, X. Y. Wang, H. L. Dong, J. Gao. Dang Gui Bu Xue Tang, a conventional Chinese herb decoction, ameliorates radiation-induced heart diseasevia Nrf2/HMGB1 pathway. Frontiers in Pharmacology. 2023;13:1086206.
6. M. Z. Cai, Y. M. Wang, T. T. Liu, Y. F. Huang*. Interaction between Vitamin D Status and Calcium Intake in Association with Blood Pressure and Hypertension. Journal of Nutritional Science and Vitaminology. 2023;69(2):81–9.
7. Y. F. Huang, G. Wang, T. Q. Peng. Calpain Activation and Organ Failure in Sepsis: Molecular Insights and Therapeutic Perspectives. Shock. 2021;56(1):5–15.
8. B. N. Chen, Y. F. Huang, D. Zheng, R. Ni, M. A. Bernards. Dietary Fatty Acids Alter Lipid Profiles and Induce Myocardial Dysfunction without Causing Metabolic Disorders in Mice. Nutrients. 2018;10(1):106.
9. X. Yang, Y. F. Huang, C. H. Sun, J. Li. Maternal Prenatal Folic Acid Supplementation Programs Offspring Lipid Metabolism by Aberrant DNA Methylation in Hepatic and Adipose in Rats. Nutrients. 2017;9(9):935.
10. M. Cai, Y. Huang, X. Sun, Y. He, C. Sun. Siesta is associated with reduced systolic blood pressure level and decreased prevalence of hypertension in older adults. Journal of Human Hypertension. 2016;30(3):216–8.
11. Y. F. Huang, T. T. Liu, C. H. Sun. Little beneficial effect of maternal vitamin supplement on metabolic disturbances in the offspring from the obese mother mice. Journal of Maternal-Fetal & Neonatal Medicine. 2015;28(3):272–5.
12. Y. F. Huang, Y. H. He, X. W. Sun, Y. J. He, Y. Li, C. H. Sun. Maternal High Folic Acid Supplement Promotes Glucose Intolerance and Insulin Resistance in Male Mouse Offspring Fed a High-Fat Diet. International Journal of Molecular Sciences. 2014;15(4):6298–313.
13. Y. F. Huang, X. X. Li, M. Q. Wang, H. Ning, A. Lima, Y. Li, C. H. Sun. Lipoprotein lipase links vitamin D, insulin resistance, and type 2 diabetes: a cross-sectional epidemiological study. Cardiovascular Diabetology. 2013;12(1):17.
（以上内容系教师个人提供）