莫兴波

发布时间:2016-04-21  浏览次数:1587

姓名:莫兴波(1983.5 -),男,广西桂平人;职称:副教授

1.学习经历
2008.07-2013.07
,北京协和医学院,遗传学,博士研究生;

2004.09-2008.07,武汉大学,数学与统计学院,基础数学,经济学,大学本科;

2.工作经历和任职情况
2013.08-2018.
06
,苏州大学,医学部公共卫生学院,讲师。
201
8.07-
,苏州大学,医学部公共卫生学院,副教授。

3.研究方向

 复杂疾病遗传流行病学、基因组学,遗传统计与生物信息学,医学统计学


4.承担课题情况

  1.  苏州大学引进人才科研启动费。

  2.  中国博士后基金二等资助,课题为类风湿性关节炎相关lncRNA鉴定及功能机制研究。

  3.  国家自然科学基金青年基金,课题为lncRNA在类风湿性关节炎中的调控网络及分子功能机制。

  4.  指导医学部学生课外科研项目,课题为验证差异表达的lncRNARA的关系。

  5.  江苏省高等学校自然科学研究面上项目,E2F3IT1作为类风湿关节炎新型标志物的评价研究。


5.发表论文

 已在Osteoporosis International, Front Genet, Epigenomics, Pharmacogenomics journal, Atherosclerosis等国际权威杂志发表相关学术论文10余篇,其中包括第一作者SCI文章16篇。

 代表性论文:

1Mo X, Zhang H, Zhou Z, Zhu Z, HuangFu X, Xu T, Wang A, Guo Z, Zhang Y. SNPs rs10224002 in PRKAG2 may disturb gene expression and consequently affect hypertension. Mol Biol Rep. 2019 Jan 28. doi: 10.1007/s11033-019-04610-3.

2Mo XB, Wu LF, Lu X, Zhu XW, Xia W, Wang L, He P, Bing PF, Zhang YH, Deng FY, Lei SF*. Detection of lncRNA-mRNA interaction modules by integrating eQTL with weighted gene co-expression network analysis. Funct Integr Genomics. 2018 Oct 2. doi: 10.1007/s10142-018-0638-4.

3Mo X, Lei S, Zhang Y, Zhang H*. Genome-wide enrichment of m6A-associated single-nucleotide polymorphisms in the lipid loci. Pharmacogenomics J. 2018 Sep 27. doi: 10.1038/s41397-018-0055-z.

4Mo XB, Wu LF, Cai XM, Tang ZX, Lu X, Zhang YH, Deng FY, Lei SF. Integrative analysis identified mediation effects of lncRNAs on the correlations between methylation and mRNA. Int J Biochem Cell Biol. 2018 Nov;104:66-72. doi: 10.1016/j.biocel.2018.09.005.

5Mo XB, Lei SF, Zhang YH, Zhang H. Detection of m6A-associated SNPs as potential functional variants for coronary artery disease. Epigenomics. 2018 Oct;10(10):1279-1287. doi: 10.2217/epi-2018-0007.

6Mo XB, Zhang YH, Lei SF. Genome-Wide Identification of N6-Methyladenosine (m6A) SNPs Associated With Rheumatoid Arthritis. Front Genet. 2018 Aug 3;9:299.

7Mo XB, Zhang YH, Lei SF. Genome-wide identification of m6A-associated SNPs as potential functional variants for bone mineral density. Osteoporos Int. 2018 Sep;29(9):2029-2039. doi: 10.1007/s00198-018-4573-y.

8Mo X, Zhang H, Lei S, Xu T, Wang A, Guo Z, Zhang Y. Putative functional SNPs in SLC22A3 and H3F3B might influence the development of CAD by regulating the lipid levels. Thromb Res. 2018 Jun 2;168:37-39.

9莫兴波, 张永红*,基于多组学的心血管疾病危险因素研究. 中华疾病控制杂志,2018,22(9):873-879.

10Mo XB, Wu LF, Zhu XW, Xia W, Wang L, He P, Bing PF, Lu X, Zhang YH, Deng FY, Lei SF. Identification and evaluation of lncRNA and mRNA integrative modules in human peripheral blood mononuclear cells. Epigenomics. 2017 Jul;9(7):943-954.

11Zhang H, Mo X*, Xu T, Bu X, Lei S, Zhang Y. Detecting novel genes for low-density lipoprotein cholesterol in European population using bioinformatics analysis. Personalized Medicine. 2016 Jan, 13(3): 225-231.

12Mo X, Zhang H, Xu T, Bu X, Lei S, Zhang Y*. Identification of important genes associated with total cholesterol using bioinformatics analysis. Pharmacogenomics. 2016 Feb;17(3):219-30.

13Zhang H#, Mo X#, Xu T, Bu X, Lei S, Zhang Y*. Novel Genes Affecting Blood Pressure Detected via Gene-Based Association Analysis. G3: Genes, Genomes, Genetics; 2015 Mar 26;5(6):1035-42.

14Mo X, Lu X, Zhang Y, Zhang Z, Deng F, Lei S*. Gene-Based Association Analysis Identified Novel Genes Associated with Bone Mineral Density. PLoS One. 2015 Mar 26;10(3):e0121811.

15Mo X#, Liu X#, Wang L, Li H, Lu X, Huang J, Chen J, Cao J, Li J, Chen S, Tang Y, Peng X, Gu D*. Lipoprotein lipase gene polymorphism rs1059611 functionally influences serum lipid concentrations. Atherosclerosis. 2013; 229(2):511-516.

16Mo X, Liu X, Wang L, Lu X, Chen S, Li H, Huang J, Chen J, Cao J, Li J, Tang Y, Gu D*. Association of lipoprotein lipase polymorphism rs2197089 with serum lipid concentrations and LPL gene expression. J Hum Genet. 2013; 58(3):160-164.

17Mo X, Hao Y, Yang X, Chen S, Lu X, Gu D*. Association between polymorphisms in the coagulation factor VII gene and coronary heart disease risk in different ethnicities: a meta-analysis. BMC Medical Genetics. 2011; 12:107.

18)莫兴波,顾东风*. 基因型填补的原理与方法及其在遗传流行病学研究中的应用.中华流行病学杂志. 2010; 31(6):702-706.


6获奖情况

  1. 苏州大学第十六届青年教师课堂教学竞赛三等奖,苏州大学,201711

  2. 苏州大学2017届毕业实习优秀实习指导教师,苏州大学教务部,2017627

  3. 优秀社会服务工作奖,苏州大学医学部公共卫生学院,201718

  4. 优秀科研工作奖,苏州大学医学部公共卫生学院,2019111


7教学工作

 承担《趣味统计》,《生物文献检索》,《医学统计学》,《卫生经济学》,《SAS统计软件包》等课程的教学工作。


8. 联系方式

 联系电话:0512-65883227          邮件:xbmo@suda.edu.cn


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